Here is a list of AMD Eyefinity Validated Software
AMD Eyefinity Validated PC Game Titles:Validation is AMD's highest award of quality. Validated products undergo extensive synthetic and real-world testing to help ensure a good customer experience. Validated products include components, and software that are critical for an optimal experience with ATI Eyefinity Technology. For the best assurance of quality, interoperability and a positive user experience, choose a Validated product.
Aliens vs. Predator
Anno 1404 (aka Dawn of Discovery)
Assassin’s Creed 2
Battlefield Bad Company 2
BattleForge
Dawn of War 2 (Warhammer 40K)
Dawn of War 2: Chaos Rising
Dirt 2
Dragon Age Origins: Awakening
Dragon Age: Origins
Elder Scrolls IV: Oblivion
Just Cause 2
Medal of Honor Multiplayer
Need for Speed: Shift
Portal
Prince of Persia: The Forgotten Sands
Team Fortress 2
The Godfather 2
Tom Clancy’s HAWX
World of Warcraft (plus expansions)